Arshad Mahmood, Ph.D

Assistant Professor

Abu Dhabi Campus

+971 2 6133549

Arshad.mahmood@aau.ac.ae

Education

Doctor of Philosophy (Pharmaceutical Technology), Leopold-Franzens-Universität Innsbruck, Austria.

Master of Philosophy (Pharmaceutics), The Islamia University of Bahawalpur, Pakistan.

Bachelor of Pharmacy, The Islamia University of Bahawalpur, Pakistan.

Research Interests

  • Mucosal drug delivery
  • Multifunctional excipients e.g. Thiomers, Phosphorylated polymers, CPP conjugates
  • Novel nano and micro carriers e.g. nanoparticles/microparticles/micells/SEDDS  with mucoadhesive, mucus penetrating, zeta potential changing, cell penetrating properties
  • Oral peptide delivery

Selected Publications

Novel biodegradable pH-sensitive hydrogels: An efficient controlled release system to manage ulcerative colitis

Mudassir Abbasi, Muhammad Sohail, Muhammad Usman Minhas, Shahzeb Khan, Zahid Hussain, Arshad Mahmood, Syed Ahmed Shah, Mubeen Kousar.

International Journal of Biological Macromolecules, 2019, 136, 83-96.

 

SEDDS: A game changing approach for the oral administration of hydrophilic macromolecular drugs

Arshad Mahmood, Andreas Bernkop-Schnürch

Advanced Drug Delivery Reviews, 2019, 142, 91-1010.

 

S-protected thiolated cyclodextrins as mucoadhesive oligomers for drug delivery

Mulazim Hussain Asim, Ali Moghadam, Muhammad Ijaz, Arshad Mahmood, Roman Xaver Götz,

Barbara Matuszczak, Andreas Bernkop-Schnürch

Journal of Colloid and Interface Science, 2018, 531, 261–268.

 

Synthesis and Characterization of Thiolated PVP−Iodine Complexes: Key to Highly Mucoadhesive Antimicrobial Gels

Aamir Jalil, Barbara Matuszczak, Nguyet-Minh Nguyen Le, Arshad Mahmood, Flavia Laffleur and Andreas Bernkop-Schnürch

Molecular Pharmaceutics, 2018, 15, 3527−3534.

 

Non-ionic thiolated cyclodextrins – the next generation

Ali Moghadam, Muhammad Ijaz, Mulazim Hussain Asim, Arshad Mahmood, Max Jelkmann, Barbara Matuszczak, Andreas Bernkop-Schnürch

International Journal of Nanomedicine, 2018, 13, 4003–4013.

 

Nasal patches containing naphazoline for management of nasal impairments

Flavia Laffleur , Benedikt Strasdat, Arshad Mahmood, Tobias Reichenberger , Melanie Gräber , Kesinee Netsomboon

Journal of Drug Delivery Science and Technology, 2018 .

 

pH-responsive CAP-co-poly(methacrylic acid)-based hydrogel as an efficient platform for controlled gastrointestinal delivery: fabrication, characterization, in vitro and in vivo toxicity evaluation

Syed Ahmed Shah, Muhammad Sohail, Muhammad Usman Minhas, Nisar-ur-Rehman, Shahzeb Khan, Zahid Hussain, Mudassir, Arshad Mahmood, Mubeen Kousar and Asif Mahmood

Drug Delivery and Translational Research, 2018.

 

Protease-functionalized mucus penetrating microparticles: In-vivo evidence for their potential

Arshad Mahmood, Gintare Leonaviciute, Flavia Laffleur and Andreas Bernkop-Schnürch

International Journal of Pharmaceutics, 2017, 532(1):177-184.

 

Thiolated chitosan micelles: Highly mucoadhesive drug carriers

Arshad Mahmood, Melanie Lanthaler, Flavia Laffleur, Christian W. Huck and Andreas Bernkop-Schnürch

Carbohydrate Polymers, 2017, 167, 250-258.

 

Zeta potential changing nanoparticles conjugated with cell penetrating peptides for enhanced transfection efficiency

Wongsakorn Suchaoin, Arshad Mahmood, Kesinee Netsomboon and Andreas Bernkop-Schnürch

Nanomedicine, 2017, 12 (9): 963-975.

 

Improved Mucoadhesive Properties of Self-nanoemulsifying Drug Delivery Systems (SNEDDS) by Introducing Acyl Chitosan

Nuri Ari Efiana, Arshad Mahmood, Hung Thanh Lam, Ožbej Zupančič, Gintare Leonaviciute and Andreas Bernkop-Schnürch

International Journal of Pharmaceutics, 2017, 519(1-2): 206–212.

 

Can thiolation render a low molecular weight polymer of just 20-kDa mucoadhesive?

Arshad Mahmood, Sonja Bonengel, Flavia Laffleur, Muhammad Ijaz, Muneeb Ahmad Idrees, Shah Hussain, Christian W. Huck, Barbara Matuszczak and Andreas Bernkop-Schnürch

Drug Development and Industrial Pharmacy, 2016, 42(5): 686-93.

 

Cell-penetrating self-nanoemulsifying drug delivery systems (SNEDDS) for oral gene delivery

Arshad Mahmood, Felix Prüfert, Nuri Ari Efiana, Muhammad Imtiaz Ashraf, Martin Hermann, Shah Hussain and Andreas Bernkop-Schnürch.

Expert Opinion on Drug Delivery, 2016, 13(11): 1503-1512.

 

Thiolated cyclodextrin: Development of a mucoadhesive vaginal delivery system for acyclovir.

Muhammad Ijaz,  Julia Anita Griessinger, Arshad Mahmood, Flavia Laffleur and Andreas Bernkop-Schnürch.

Journal of Pharmaceutical Sciences, 2016, 105: 1714–1720.

 

Charge changing phosphorylated polymers: Proof of in situ mucoadhesive properties.

Sonja Bonengel, Max Jelkmann, Oh Sejin, Arshad Mahmood, Muhammad Ijaz and Andreas Bernkop-Schnurch

European Journal of Pharmaceutics and Biopharmaceutics, 2016, 105: 203–208.

 

S-protected thiolated hydroxyl ethyl cellulose (HEC): novel mucoadhesive excipient with improved stability.

Gintare Leonaviciute, Sonja Bonengel, Arshad Mahmood, Muneeb Ahmad Idrees and Andreas Bernkop-Schnürch

Carbohydrate Polymers, 2016, 144: 514–521.

 

Preactivated thiolated pullulan as a versatile excipient for mucosaldrug targeting

Gintare Leonaviciute, Wongsakorn Suchaoin, Barbara Matuszczak, Hung Thanh Lam, Arshad Mahmood and Andreas Bernkop-Schnürch

Carbohydrate Polymers, 2016, 151: 743–751.

 

In vitro and ex vivo evaluation of biomaterials' distinctive properties as a result of thiolation.

Flavia Laffleur, Julian Wagner, Arshad Mahmood

Future Medicinal Chemistry, 2016, 7(4): 449–457.

 

An in-vitro exploration of permeation enhancement by novel polysulfonate thiomers

Arshad Mahmood, Sonja Bonengel, Flavia Laffleur, Muhammad Ijaz, Gintare Leonaviciute and Andreas Bernkop-Schnürch

International Journal of Pharmaceutics, 2015, 496(2): 304–313.

 

Synthesis and characterization of thiolated β-cyclodextrin as a novel mucoadhesive excipient for intra-oral drug delivery

Muhammad Ijaz, Barbara Matuszczak, Deni Rahmat, Arshad Mahmood, Sonja Bonengel, Shah Hussain, Christian W. Huck and Andreas Bernkop-Schnürch.

Carbohydrate Polymers, 2015, 132: 187–195.

 

Effect of β-Glucuronidase on Extraction Efficiency of Silymarin from Human Plasma Samples Using Validated HPLC-UV Analysis”

Muhammad Usman, Mahmood Ahmad, Abdullah Dayo, Asadullah Madni, Liaqat Ali, Muhammad Yousuf, Mahtab Ahmad Khan, Abubakar Munir, Muhammad Sohail and Arshad Mahmood

Tropical Journal of Pharmaceutical Research; 2012 11 (1): 84-90.

Conferences

Transport of self-nanoemulsifying drug delivery system (SNEDDS) across mucus and cellular internalization

Arshad Mahmood and Andreas Bernkop-Schnürch

OMICS International European Pharma Congress, 25-27 August 2015, Valencia, Spain.

 

Overcoming the mucosal barrier via proteolytic enzyme decorated nano- and microcarriers

Arshad Mahmood

Ist International Basic Medical Sciences Conference (BMedCon 2018), Khyber Medical University, 23rd-25th October, 2018, Peshawar, Pakistan.

Professional Experience

  • Al Ain University, Abu Dhabi campus, Abu Dhabi, UAE.              

September 2019 till date

As Assistant Professor

  • COMSATS Institute of Information Technology, Abbottabad, Pakistan.

January 2018 to September 2019

As Assistant Professor

  • COMSATS Institute of Information Technology, Abbottabad, Pakistan                

September 2010 to December 2017 (Study leave for PhD March 2013- April 2017)

As Lecturer                                                    

  • The University Of Lahore (Islamabad Campus), Islamabad Pakistan                           

July 2008 To September 2010

As Lecturer

  • Global Pharmaceuticals (Pvt) Ltd. Islamabad, Pakistan                 

February 2005 to March 2006

As Quality Assurance Officer

Teaching Courses

  • Physical pharmacy,
  • Biopharmaceutics and pharmacokinetics,
  • Medication dispensing and distribution systems.

Memberships

  • Pharmacy Council of Pakistan.