Biography

Head of Postgraduate and Research Affairs Committee and Faculty Member

 

Research Achievement by Nov 2024:

• Scholar no. 762 in the UAE Top Scientists List - AD Scientific Index
• Scholar no. 426,140 in the World Top Scientists List - AD Scientific Index 
• h-index 21 - Google Scholar
• 2070 citations - Google Scholar
• 4246.4 RI Score 99% of higher ResearchGate members 
• 55 publications in Scopus 

 

  A proven track record in securing research funding:

• Co-pi: Mosab Arafat , Grant awarded: Jan 2020, Propsal no. 1270, (Research Start- up grant no: 700032854 ), Agency awarded: UAEU. Project duration: 2 years, Grant Amount of AED  400,000 equivalent to (~110,000 USD). 
• PI: Mosab Arafat, Grant awarded: 2018, Agency awarded: Al Ain University, Grant Amount of AED  400,000 equivalent to (~110,000 USD).
• PI: Mosab Arafat, Grant awarded: 2021, Agency awarded: Al Ain University, Grant Ph2021-2-902.
• PI: Mosab Arafat, Grant awarded: 2024, Agency awarded: Al Ain University, Grant Ph2024

Education

Ph.D. Nanomedicines, University of Otago, School of Pharmacy, New Zealand

MSc. Pharmaceutics, School of Pharmaceutical sciences

B.Pharm. Faculty of Pharmacy

Research Interests

Nanoparticle formulation of drugs and delivery of bioactive molecules for human. Development, preparation, characterization and stability evaluation of nano-colloidal drug delivery systems (Bilosomes, Liposomes & Niosomes). In vivo & in vitro evaluation of drug molecules loaded in nano-particles using animals/humans. Development of analytical methods for drug molecules and metabolic studies using HPLC and LC-MS.

Selected Publications

1. Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment-A Recent Review.
   Arafat M, Sakkal M, Beiram R, AbuRuz S.Pharmaceuticals (Basel). 2024 Feb 28;17(3):315. doi: 10.3390/ph17030315.PMID: 38543101 Free PMC article. .
2. Effect of Hydration Forms and Polymer Grades on Theophylline Controlled-Release Tablet: An Assessment and Evaluation.
   Sakkal M, Arafat M, Yuvaraju P, Beiram R, Ali L, Altarawneh M, Hajamohideen AR, AbuRuz S.Pharmaceuticals (Basel). 2024 Feb 21;17(3):271. doi: 10.3390/ph17030271.PMID: 38543057 Free PMC article.
3. Preparation and Characterization of Theophylline Controlled Release Matrix System Incorporating Poloxamer 407, Stearyl Alcohol, and Hydroxypropyl Methylcellulose: A Novel Formulation and Development Study.
   Sakkal M, Arafat M, Yuvaraju P, Beiram R, AbuRuz S.Polymers (Basel). 2024 Feb 27;16(5):643. doi: 10.3390/polym16050643.PMID: 38475326
4. Resveratrol-Laden Nano-Systems in the Cancer Environment: Views and Reviews.
   Sarfraz M, Arafat M, Zaidi SHH, Eltaib L, Siddique MI, Kamal M, Ali A, Asdaq SMB, Khan A, Aaghaz S, Alshammari MS, Imran M.Cancers (Basel). 2023 Sep 10;15(18):4499. doi: 10.3390/cancers15184499.PMID: 37760469
5. Enteric-coating film effect on the delayed drug release of pantoprazole gastro-resistant generic tablets.
   Arafat M, Sakkal M, Bostanudin MF, Alhanbali OA, Yuvaraju P, Beiram R, Sadek B, Akour A, AbuRuz S.F1000Res. 2023 Oct 12;12:1325. doi: 10.12688/f1000research.140607.1. eCollection 2023.PMID: 38596002
6. Effect of Excipients on the Quality of Drug Formulation and Immediate Release of Generic Metformin HCl Tablets.
   Arafat M, Sakkal M, Yuvaraju P, Esmaeil A, Poulose V, Aburuz S.Pharmaceuticals (Basel). 2023 Apr 4;16(4):539. doi: 10.3390/ph16040539.PMID: 37111296
7. Formulation and In-Vitro Characterisation of Cross-Linked Amphiphilic Guar Gum Nanocarriers for Percutaneous Delivery of Arbutin.
   Bostanudin MF, Salam A, Mahmood A, Arafat M, Kaharudin AN, Sahudin S, Mat Lazim A, Azfaralariff A.J Pharm Sci. 2021 Dec;110(12):3907-3918. doi: 10.1016/j.xphs.2021.08.014. Epub 2021 Aug 14.PMID: 34403653
8. Development and In Vitro Evaluation of Controlled Release Viagra® Containing Poloxamer-188 Using Gastroplus™ PBPK Modeling Software for In Vivo Predictions and Pharmacokinetic Assessments.
   Arafat M, Sarfraz M, AbuRuz S.Pharmaceuticals (Basel). 2021 May 18;14(5):479. doi: 10.3390/ph14050479.PMID: 34070160
9. In Vitro and In Vivo Evaluation of Oral Controlled Release Formulation of BCS Class I Drug Using Polymer Matrix System.
   Arafat M, Sarfraz M, Bostanudin MF, Esmaeil A, Salam A, AbuRuz S.Pharmaceuticals (Basel). 2021 Sep 16;14(9):929. doi: 10.3390/ph14090929.PMID: 34577629
10. Nanosized Liposomes Containing Bile Salt: A Vesicular Nanocarrier for Enhancing Oral Bioavailability of BCS Class III Drug.
    Arafat M, Kirchhoefer C, Mikov M, Sarfraz M, Löbenberg R.J Pharm Pharm Sci. 2017;20(0):305-318. doi: 10.18433/J3CK88.PMID: 28885915

Conferences

1. Mosab Arafat, Sarfraz M, Kirchhoefer C, öbenberg R. Studying vesicles membrane stability of nanotransfersomes containing bile salts using calcein as a marker for stability. The Americana Association of Pharmaceutical Scientists Journal. AAPS Annual Meeting and Exposition. November 3-6, 2019. San Antonio, Texas, USA   
2. Mosab Arafat, C. Kirchhoefer, Sarfraz M, Löbenberg R. Study the Effect of Physiological Fluid on Vesicles Membrane Stability of Liposomes containing Bile Salts using Calcein as a Marker for Vesicles Leakage. The Americana Association of Pharmaceutical Scientists Journal. AAPS Annual Meeting and Exposition. November 4-7, 2018. Washington DC, USA.
3. Mosab Arafat, Kirchhoefer C, Mikov M.  Nano-Mixed Micelles: An Approach to Enhance the Oral Bioavailability of BCS Class III Drug.  14th International Conference and Exhibition on Nanomedicine and Pharmaceutical Nanotechnology. Apr 2018. Amsterdam, Netherland.
4. Mosab Arafat, Kirchhoefer C, Mikov M, Sarfraz M, Löebenberg R. The enhancement of the poor oral bioavailability of cefotaxime sodium using nano-mixed micelles formulation. Canadian Society for Pharmaceutical Sciences. 2018 CSPS Annual Symposium. May 22 – 25, 2018. Toronto, Canada.
5. Khalid N, Sarfraz M, Mosab Arafat, Akhtar M, Rahman N, Löebenberg R. Nano-sized Droplets of Self-emulsifying System for Enhancing Oral Bioavailability of Etoposide in Rats.Canadian Society for Pharmaceutical Sciences. 2018 CSPS Annual Symposium. May 22 – 25, 2018. Toronto, Canada.
6. Mosab Arafat,  Sarfraz M, Kirchhoefer C, Mikov M., Löbenberg R. Dual Effect of Bile Salts in Nanocarriers: Counteracting Gastrointestinal Lysis and Enhancing The Oral Bioavailability of BCS Class III Drug. The Americana Association of Pharmaceutical Scientists Journal. AAPS Annual Meeting and Exposition. November 12-15, 2017. San Diego, California, USA.
7.  Mosab Arafat, Paul Fawcett, Ian G Tucker. The effect of bile salt content on the physical stability of bilosomes. The  Americana Association of Pharmaceutical Scientists Journal. 2009; 11 (S1). AAPS Annual Meeting and Exposition. Los Angeles, California, USA

8.  Mosab Arafat, Paul Fawcett, Hu Zhang, Ian G Tucker. The oral bioavailability of cefotaxime in a bilosome formulation in rats. The Americana Association of Pharmaceutical Scientists Journal. 2011; 13 (S2). AAPS Annual Meeting and Exposition. San Francisco, California, USA

9. Mosab Arafat, Paul Fawcett, Ian G Tucker. The Influence of Physiological Media on The Stability of Bilosomes. The Americana Association of Pharmaceutical Scientists Journal; 2011; 13 (S2). AAPS Annual Meeting and Exposition.Washington DC, USA

10. Mosab Arafat, Paul Fawcett, Ian G Tucker. The influence of different media on the physical stability of different lipid-based vesicular systems. The Americana Association of Pharmaceutical Scientists Journal. 2011; 13 (S1). AAPS Annual Meeting and Exposition.Washington DC, USA

Teaching Courses

1. Pharmaceutics I
2. Pharmaceutics II
3. Pharmaceutics III
4. Physical Pharmacy
5. Medication Dispensing
6. Pharmaceutical Calculation
7. Industrial Pharmacy

 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all.

This person’s work contributes towards the following SDG(s):

  

 

Memberships

 

1. Associate Editor of Advancements in Bioequivalence & Bioavailability Journal (Crimson Publishers, LLC) - Regus - New York, USA
2. Member of American Association Pharmaceutical Scientists (AAPS).
3. Editorial board member of SOJ Pharmacy & Pharmaceutical Sciences (Open Access American Journal) - Illinois USA
4. Editorial board member Global Drug and Therapeutics (Open Access Journal) - London, UK
5. A reviewer of Current Pharmacy Analysis (Bentham Science Publisher) - Netherlands 
6. Editorial board member of Open Access Journal of Pharmaceutical Research (Open Access Journal) - USA 
7. Editorial board member of EC Pharmacology and Toxicology journal (Open Access Journal) - UK

8. Editorial board member of SOJ Pharmaceutical Sciences (Open Access American Journal) - Minden, NV, USA

9. Editorial board member of Thermal Science and Engineering (EnPress Journal) - USA
10. Peer Review Panel (PRP) Members for abstracts submitted to Controlled Release Society (CRS) 45th Annual Meeting and Exposition, New York, New York City (NYC), USA