Discovery of novel thiazole derivatives containing pyrazole scaffold as PPAR-γ Agonists, α-Glucosidase, α-Amylase and COX-2 inhibitors; Design, synthesis and in silico study
Published in: Bioorganic Chemistry
Nov 01, 2024
Prefrontal coding of learned and inferred knowledge during REM and NREM sleep
Published in: Nature Communications
Jun 24, 2024
Uncovering the role of RNA binding proteins in the ER stress response in pancreatic beta cells
Published in: Diabetes UK Professional Conference
Apr 16, 2024
Uncovering the role of RNA binding proteins in the ER stress response in pancreatic beta cells TP Herbert1, A Al-Bazaz1, C Charoensuk1, R Al-Momani1, W See1, R Barnes1, J Whitehead2, D Boocock3 1School of Pharmacy, University of Lincoln, Lincoln, UK; 2School of Life and Environmental Sciences, University of Lincoln, Lincoln, UK; 3John van Geest Cancer Research Centre, Nottingham Trent University, Nottingham, UK Aim: Chronic ER stress is implicated in the development of beta cell dysfunction ...
The identification of ‘secretory’ RNA-binding proteins (RBPs) provides evidence for a hitherto unknown link between gene expression and insulin exocytosis
Published in: Diabetes UK Professional Conference
Apr 16, 2024
The identification of ‘secretory’ RNA-binding proteins (RBPs) provides evidence for a hitherto unknown link between gene expression and insulin exocytosis R Almomani1, R Wardman1, C Charoensuk1, T Sekaran2, T Schwarzl2, I Huppertz2, J Whitehead1, D Hodson3, M Hentze2, TP Herbert1 1School of Pharmacy and Life Sciences, University of Lincoln, Lincoln, UK; 2European Molecular Biology Laboratory, Heidelberg, Germany; 3Medical Sciences Division, University of Oxford, Oxford, UK Aims: The aims of ...
Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFRWT/T790M and PI3k enzymes; Design, Synthesis, biological Evaluation, and docking studies
Published in: Bioorganic Chemistry
Apr 01, 2024
A short-term memory trace persists for days in the mouse hippocampus
Published in: Communications Biology
Nov 03, 2022
Selective engram coreactivation in idling brain inspires implicit learning
Published in: Proceedings of the National Academy of Sciences (PNAS)
Aug 09, 2022
Levels of vitamin D and vitamin D pathway gene polymorphisms in adults: Results based on rural agriculture workers in Punjab province of Pakistan
Published in: https://www.mattioli1885journals.com/index.php/progressinnutrition/article/view/8180
Oct 01, 2020
Background and aims: Worldwide low levels of vitamin D (< 30ng/dL) is prevalent and linked to bone disorders, diabetes and coronary heart disease. Deficiency in Vitamin D is a diagnostic challenge in asymptomatic individuals. The present study aimed to assess the environmental and also the genetic determinants affecting vitamin D deficiency in an asymptomatic rural agricultural population sample of Punjab province of Pakistan. Material and method: An interview based questionnaire and blood samp...