Osteoporosis Related Knowledge and Attitudes: The Scenario in Tripoli, Libya

Abstract: Background: Osteoporosis is a worldwide disease, which is characterized by a reduction in bone mass and alteration of its architecture that increases bone fragility and the risk of fracture. Objective: This study aimed to assess knowled...

Molecualr modelling studies on alpha-7 nicotinic receptor allosteric modulators yields novel filter-based virtual screening protocol

The ɑ7 receptor is a member in the nicotinic acetylcholine receptor (nAChR) which has been implicated in several neurological disorders. Beside normal agonists and antagonists of α7 nAChRs, several studies revealed other types of molecules that are ...

The choice of pharmacy profession as a career: UAE experience

The hypoglycemic effect of Libyan Truffle (Terfezia Boudieri) in experimentally induced diabetic rats.

Recent studies have shown that many types of mushrooms may have important physiological functions in humans including antioxidant activities, regulation of blood lipid level and blood glucose level. The present study was designed to investigate the ...

Anti-inflammatory agents of the carbamoylmethyl ester class: synthesis, characterization, and pharmacological evaluation

Abstract: In this study, target compounds 5–12 were synthesized via acid amine coupling of ibuprofen and naproxen with methyl ester derivatives of amino acids, namely, l-proline, sarcosine, l-tyrosine, and l-glutamic acid. When tested for anti-infla...

Prescribing Patterns of Selected Agents at General Medicine Department, Tripoli Central Hospital, Libya

Risk calculation of developing type 2 diabetes in Libyan adults

The aim of this study was to identify nationals at risk of developing type 2 diabetes within the next 10 years in some areas across Tripoli Health Authority in Libya. In this questionnaire-based survey, a total of 400 Libyan nationals of both gender...

Synthesis of 5-hydroxy-2,3,4,5-tetrahydro-[1H]-2-benzazepin-4-ones: Selective antagonists of muscarinic (M3) receptors

Two approaches to tetrahydro-[1H]-2-benzazepin-4-ones of interest as potentially selective, muscarinic (M(3)) receptor antagonists have been developed. Base promoted addition of 2-(tert-butoxycarbonylamino)methyl-1,3-dithiane with 2-(tert-butyldimet...

Investigation of the mechanism for the relaxation of rat duodenum mediated via M1 muscarinic receptors

1 Relaxation responses of the rat isolated duodenum to the putative M1 muscarinic receptor agonist, McN-A-343, were examined to determine whether the response was due to the release of known non-adrenergic, non-cholinergic relaxant neurotransmitters...